Table 1. Quantitative parameters of the proposed and reported methods for CMB detection.

Method	Linear range (μM)	LOD (μM)	Cost	Time	Complexity	Interference risk	Reference
HPLC-DAD	0.048–242.7	0.009	High	Slow	High	Moderate	7
HPLC-FLD	0.05–9.5	—	High	Slow	High	Moderate	36
UPLC-MS/MS	0.002–7.28	—	Very high	Slow	Very high	Low	37
Au@PAB/CNFs	0.01–20	0.005	Medium	Moderate	Moderate	Low to moderate	38
CeNPs@CNF-CF	—	0.05	Medium	Moderate	Moderate	Low to moderate	39
CeNPs@CNF-CF/PGRE	0.005–0.97	0.0014	Medium	Moderate	Moderate	Low to moderate	40
Spectrofluorometry	0.04–4.85	0.009	Low	Fast	Simple	High (plasma proteins)	7
	0–480	0.0036	Low	Fast	Simple	Minimal	This work