Fig. 2.

Volcano plot and heatmap demonstrating the deregulated expression of proteins after ICH. The volcano plots (A) and (B) denote the distribution of DEPs in aged male and female subjects, respectively, with the horizontal dotted line representing the p-value of 0.05, and all proteins above that line are significantly deregulated after ICH compared to sham. The heat maps (generated using http://www.heatmapper.ca), (C), and (D) illustrate the expression pattern of DEPs in aged male and female subjects, respectively (n = 4–5/group).