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. Author manuscript; available in PMC: 2025 Aug 25.
Published in final edited form as: Cell. 2025 Jun 26;188(13):3389–3404.e6. doi: 10.1016/j.cell.2025.04.027

KEY RESOURCES TABLE.

REAGENT or RESOURCE SOURCE IDENTIFIER

Deposited data

LASI-DAD Whole Genome Sequence NIAGADS https://dss.niagads.org/datasets ng00067
LASI-DAD Individual level summary statistics NIAGADS https://dss.niagads.org/datasets ng00171
1000 Genomes Whole Genome Sequence IGSR https://www.internationalgenome.org/data
Human Genome Diversity Project Whole Genome Sequence IGSR https://www.internationalgenome.org/data-portal/data-collection/hgdp
GenomeAsia Pilot project Whole Genome Sequence European Genome Archive EGAS00001002921
Allen Ancient DNA Resource https://dataverse.harvard.edu/dataset.xhtml?persistentId=doi:10.7910/DVN/FFIDCW v54
RefSeq database RefSeq https://www.ncbi.nlm.nih.gov/refseq/
ClinVar database ClinVar https://www.ncbi.nlm.nih.gov/clinvar/; data release of 2023-12-17

Software and algorithms

BWA-mem https://github.com/lh3/bwa v0.7.15
BamUtil https://genome.sph.umich.edu/wiki/BamUtil v1.0.13
samtools https://github.com/samtools/ version 1.12-25-g4eae367
samblaster https://github.com/GregoryFaust/samblaster version 0.1.24
sambamba https://lomereiter.github.io/sambamba/ N/A
GATK https://gatk.broadinstitute.org/hc/en-us/sections/360007336992-4-0-1-1 4.1.1
KING https://www.kingrelatedness.com v2.3.0
SHAPEIT https://odelaneau.github.io/shapeit4/ 4
liftOver https://liftover.broadinstitute.org/ N/A
EIGENSOFT https://github.com/DReichLab/EIG v7.2.1
ADMIXTURE https://dalexander.github.io/admixture/ v1.3.0
PLINK https://www.cog-genomics.org/plink/2.0/ v2.00a2.3
ADMIXTOOLS https://github.com/DReichLab/AdmixTools v7.0.2
ALDER https://cb.csail.mit.edu/alder/ v1.04
hap-IBD https://github.com/browning-lab/hap-ibd N/A
Variant Effect Predictor https://github.com/Ensembl/ensembl-vep version 105
LOFTEE https://github.com/korradjk/loftee v1.0.3
hmmix https://github.com/LauritsSkov/Introgression-detection version 1.0
GeneSCF https://github.com/genescf/GeneSCF N/A
BCF tools https://samtools.github.io/bcftools/bcftools.html v1.6
VCF tools https://vcftools.github.io/index.html 0.1.16
R https://www.r-project.org version 4.4.0