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. 2025 Aug 18;69(4):e240377. doi: 10.20945/2359-4292-2024-0377

Figure 4.

Figure 4

Effects of overexpression of PON1 on the PPARγ signaling pathway in high glucose-induced HK-2 cells. (A) Convergence of PON1-associated signaling pathways with diabetic nephropathy-involved signaling pathways. (B) The expression of PPARα and PPARγ by Western blot.

*p < 0.001 versus control, p < 0.001 versus HG+pc-negative control, p < 0.01 versus high glucose +pc-PON1. HG: high glucose.