Table 3.
Clinical profile and refractoriness of patients with differentiated thyroid carcinoma
| Refractoriness | Yes | No | p-value* | |
|---|---|---|---|---|
| Sex | ||||
| Female | 40 (90.9) | 476 (93.3) | 0.54 | |
| Male | 4 (9.1) | 34 (6.7) | ||
| Age at diagnosis, years | 50 (9-83) | 44 (6-77) | < 0.01† | |
| Follow-up time, years | 8.5 (2-31) | 11.0 (1-29) | 0.58† | |
| Number of surgeries | ||||
| 1 | 19 (43.2) | 335 (65.7) | < 0.01 | |
| > 1 | 25 (56.8) | 175 (34.3) | ||
| Histology | ||||
| Papillary | 39 (90.7) | 399 (78.7) | 0.31 |
|
| Follicular | 3 (7.0) | 81 (16.0) | ||
| Oncocytic | 1 (2.3) | 22 (4.3) | ||
| Papillary histological subtype | ||||
| Classical | 24 (61.5) | 269 (67.6) | < 0.01 | |
| Follicular | 11 (28.2) | 119 (29.9) | ||
| Tall cell | 2 (5.1) | 3 (0.8) | ||
| Hobnail | 1 (2.6) | 0 (0.0) | ||
| Diffuse sclerosing | 1 (2.6) | 1 (0.3) | ||
| Others‡ | 0 (0.0) | 6 (1.7) | ||
| Tumor size, cm | 3.1 (0.1-7.0) | 2.0 (0.1-8.0) | < 0.01† | |
Results expressed as n (%) or median (minimum-maximum).
*
Fisher’s exact;
†
Mann-Whitney;
‡
solid/trabecular, columnar, clear cell and cribriform-morular.