Table 3.
Non-Hematologic Adverse Events
| Event1 | All Grades n (%) | Grade ≥3 n (%) |
|---|---|---|
| All | 46 (77) | 26 (43) |
| Infectious | 25 (42) | 22 (37) |
| All (non-infectious) | 36 (60) | 12 (20) |
| Hyperbilirubinemia | 16 (27) | 3 (5) |
| Diarrhea | 12 (20) | 1 (2) |
| Transaminitis | 9 (15) | 1 (2) |
| Acute kidney injury | 8 (13) | 0 (0) |
| Constipation | 8 (13) | 0 (0) |
| Nausea | 8 (13) | 0 (0) |
| Vomiting | 5 (8) | 1 (2) |
| Hypokalemia | 4 (7) | 0 (0) |
| Differentiation syndrome | 3 (5) | 2 (3) |
| Fatigue | 3 (5) | 0 (0) |
| Cough | 2 (3) | 0 (0) |
| Hyperphosphatemia | 2 (3) | 1 (2) |
| Hyperuricemia | 2 (3) | 0 (0) |
| QTc prolongation | 2 (3) | 1 (2) |
| Abdominal pain | 1 (2) | 1 (2) |
| Alopecia | 1 (2) | 0 (0) |
| Arthralgias | 1 (2) | 0 (0) |
| Hypomagnesemia | 1 (2) | 0 (0) |
| Hypocalcemia | 1 (2) | 0 (0) |
| Rash | 1 (2) | 0 (0) |
| Tumor lysis syndrome | 1 (2) | 1 (2) |
1
At least possibly related while on protocol