Table 3. SI of the most active compounds 6b, 7b, 8b, 12a–d and sorafenib.
| Entry | Selectivity index (SI) | ||
|---|---|---|---|
| Cell lines | A498 | HepG2 | MDA-MB-231 |
| 6b | 2.03 | 2.15 | 2.49 |
| 7b | 1.37 | 11.89 | 3.64 |
| 8b | 2.45 | 2.60 | 0.63 |
| 12a | 0.59 | 2.95 | 1.00 |
| 12b | 0.79 | 2.80 | 1.25 |
| 12c | 0.29 | 9.92 | 0.99 |
| 12d | 0.35 | 1.78 | 0.91 |
| Sorafenib | 0.014 | 0.02 | 0.011 |