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. 2025 Aug 22;15(36):29753–29776. doi: 10.1039/d5ra04997k

Table 3. SI of the most active compounds 6b, 7b, 8b, 12a–d and sorafenib.

Entry Selectivity index (SI)
Cell lines A498 HepG2 MDA-MB-231
6b 2.03 2.15 2.49
7b 1.37 11.89 3.64
8b 2.45 2.60 0.63
12a 0.59 2.95 1.00
12b 0.79 2.80 1.25
12c 0.29 9.92 0.99
12d 0.35 1.78 0.91
Sorafenib 0.014 0.02 0.011