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. 2025 Aug 22;15(36):29753–29776. doi: 10.1039/d5ra04997k

Table 7. Kinetic parameters of allopurinol and 12a against xanthine oxidase in the enzyme kinetic study.

Conc. (μM) 12a Allopurinol
K m V max K m V max
XO 40 2.25 40 2.21
0.1 75 1.66 50 1.51
1 112 1.38 64 1.33
10 123 0.98 51 0.55