Table 7. Kinetic parameters of allopurinol and 12a against xanthine oxidase in the enzyme kinetic study.
| Conc. (μM) | 12a | Allopurinol | ||
|---|---|---|---|---|
| K m | V max | K m | V max | |
| XO | 40 | 2.25 | 40 | 2.21 |
| 0.1 | 75 | 1.66 | 50 | 1.51 |
| 1 | 112 | 1.38 | 64 | 1.33 |
| 10 | 123 | 0.98 | 51 | 0.55 |
| Conc. (μM) | 12a | Allopurinol | ||
|---|---|---|---|---|
| K m | V max | K m | V max | |
| XO | 40 | 2.25 | 40 | 2.21 |
| 0.1 | 75 | 1.66 | 50 | 1.51 |
| 1 | 112 | 1.38 | 64 | 1.33 |
| 10 | 123 | 0.98 | 51 | 0.55 |