Table 5.

ROC data for LHR, MHR, NHR, and PHR predicting MASLD and significant liver fibrosis

Test	AUC	95% CI low	95% CI upper	Best threshold	Specificity	Sensitivity	P value for AUC comparison
MASLD
LHR	0.6687	0.6571	0.6802	1.6030	0.6062	0.6621	Ref.
MHR	0.6577	0.6461	0.6693	0.3741	0.5119	0.7254	0.0359
NHR	0.6659	0.6543	0.6775	2.9182	0.5785	0.6712	0.6250
PHR	0.6540	0.6423	0.6657	178.7640	0.5739	0.6648	0.0044
Significant liver fibrosis
MHR	0.6319	0.6134	0.6504	0.4581	0.5963	0.6041	Ref.
NHR	0.6256	0.6068	0.6444	2.9346	0.4935	0.7047	0.3687
LHR	0.5992	0.5795	0.6189	1.7928	0.6047	0.5699	0.0001
PHR	0.5762	0.5567	0.5957	178.9232	0.4835	0.6560	<0.0001

AUC, area under the curve; LHR, lipoprotein-cholesterol ratio; MASLD, metabolic dysfunction-associated steatotic liver disease; MHR, monocyte-HDL-C ratio; NHR, neutrophil-HDL-C ratio; PHR, platelet-HDL-C ratio; ROC, receiver operating characteristic.