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. 2025 Aug 22;15(36):29960–29971. doi: 10.1039/d5ra03877d

Table 2. Details of the important components of the active sites of AChE and BChE.

Component Sub-component Available amino acids
AChE BChE
CAS AS Trp84, Phe331, Phe330 Trp82, Tyr128, Phe329
CT Ser200, His440, Glu327 Ser198, His438, Glu325
PAS Asp72, Tyr334, Tyr121, Trp279, Tyr70 Asp70, Tyr332
Acyl pocket Phe290, Phe228 Val288, Leu286
Oxyanion hole Ala201, Gly118, Gly119 Ala199, Gly116, Gly117