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. 2025 Aug 22;15(36):29960–29971. doi: 10.1039/d5ra03877d

Table 2. Details of the important components of the active sites of AChE and BChE.

Component Sub-component Available amino acids
AChE BChE
CAS AS Trp84, Phe331, Phe330 Trp82, Tyr128, Phe329
CT Ser200, His440, Glu327 Ser198, His438, Glu325
PAS — Asp72, Tyr334, Tyr121, Trp279, Tyr70 Asp70, Tyr332
Acyl pocket — Phe290, Phe228 Val288, Leu286
Oxyanion hole — Ala201, Gly118, Gly119 Ala199, Gly116, Gly117