Table 1.
Main features of the included study population: n = 84 patients with GD or GC arisen in a histopathological background of MF-AG or CR-AG
| All patients MF-AG and CR-AG n = 84 (100%) | MF-AG n = 45 (53.6%) |
CR-AG n = 39 (46.4%) |
P | |
| Age at AG diagnosis | ||||
| Median, range | 70.0, 33–90 | 70.0, 33–90 | 70.0, 48-86 | 0.46 |
| Mean, SD | 69.3, 10.6 | 70.0, 10.8 | 68.5, 10.4 | 0.50 |
| Females, n (%) | 54.8 | 42.2 | 69.2 | 0.01 |
| GD-GC diagnosis concomitant to AG diagnosis | 35.7 | 33.3 | 38.5 | 0.63 |
| AG diagnosis >1 yr regarding GD-GC diagnosis median, range | 4, 1-17 | 4, 1-12 | 5, 1-17 | 0.90 |
| Mean, SD | 5.5, 4.0 | 5.1, 3.2 | 6.0, 4.8 | 0.54 |
| Hp eradication treatment before diagnosis of GD-GC | 16.7 | 20.0 | 12.8 | 0.30 |
| Positivity toward parietal cell autoantibodies | 60.0 | 51.5 | 69.7 | 0.13 |
| First-degree family history for GC | 15.2 | 14.7 | 15.6 | 0.92 |
| Active or previous use of proton pump inhibitors | 56.4 | 56.2 | 56.5 | 0.98 |
| Active or previous smoking habit | 30.4 | 9/30 (30.0) | 30.8 | 0.95 |
| Type of anemia | n = 31 | |||
| Iron-deficiency | 25.8 | 30.3 | 19.4 | 0.31 |
| Pernicious | 18.8 | 9.1 | 29.0 | 0.04 |
| Mixed | 9.4 | 12.1 | 6.5 | 0.44 |
| None | 46.9 | 48.5 | 45.2 | 0.79 |
Data expressed as % when not otherwise indicated.
AG, atrophic gastritis, CR, corpus-restricted; GC, gastric cancer; GD, gastric dysplasia; Hp, Helicobacter pylori; MF, multifocal.