TABLE 3.
Definition of objectives and constraints for optimized policies
| Objectives | |||
|---|---|---|---|
| Transplant system metric | Direction of improvement | ||
| Waitlist mortality | Minimize | ||
| 1-y graft failures | Minimize | ||
| Blood type transplant rate disparity | Minimize | ||
| Geographic transplant rate disparity | Minimize | ||
| Racial transplant rate disparity | Minimize | ||
| Constraints | |||
| Transplant system metric | Direction | Threshold | |
| Pediatric transplants | No less than | Current policy (1036 [Tx]) | |
| cPRA 99.9–100 transplants | No less than | Current policy (452 [Tx]) | |
| Average waiting time at transplant | No less than | Current policy (5.85 [y]) | |
| Blood type B transplants | No less than | Current policy (1806 [Tx]) | |
| Median travel distance | No greater than | Policy A2 | current policy (134 [NM]) |
| Policy B2 | 110% current policy (147 [NM]) | ||
| Policy C2 | 110% current policy (147 [NM]) | ||
| Policy D2 | 125% current policy (168 [NM]) | ||
| EPTS 0–20 transplants | No less than | Policy A2 | current policy (3888 [Tx]) |
| Policy B2 | current policy (3888 [Tx]) | ||
| Policy C2 | 97% current policy (3771 [Tx]) | ||
| Policy D2 | 97% current policy (3771 [Tx]) | ||
In this table, we present how the OPTN committee goals were represented in the optimization algorithms used to create the 4 optimized policies A2, B2, C2, and D2.
EPTS, expected posttransplant survival; NM, nautical miles; OPTN, Organ Procurement and Transplantation Network; Tx, transplant.