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. 2025 Aug 22;13:e19848. doi: 10.7717/peerj.19848

Table 2. Classification of 33 SM BGCs detected in the genome of P. paneum OM1 and the predicted SM products.

Type Number of SM gene cluster Contig number Length
(bp)
Most similar known cluster
NRPS 1 10 45,286 metachelin C/metachelin A/metachelin A-CE/metachelin B/dimerumic acid 11-mannoside/dimerumic acid
2 8 49,474 –
58,554 nidulaninA
NRPS-like 4 6 42,624 –
43,830 choline
42,181 –
44,283 –
1 9 44,331 –
NRPS-indole 1 8 52,499 paraherquamide
1 9 46,277 histidyltryptophanyldiketopiperazine/ dehydrohistidyltryptophanyldiketopiperazine/roquefortine D/ roquefortine C/glandicoline A/glandicoline B/meleagrin
NRP-metallophore (NRPS) 1 10 58,820 –
NRPS-T1PKS 1 9 52,398 chaetoglobosin A/chaetoglobosin C
T1PKS 3 10 47,971 andrastin A
49,366 –
48,164 –
5 8 47,878 –
48,387 –
46,893 –
47,300 –
49,474 –
3 9 46,052 YWA1
47,407 trichoxide
45,491 patulin
T1PKS-NRPS 1 10 53,409 ACE1
2 8 52,402 –
59,474 metachelin C/metachelin A/metachelin A-CE/metachelin B/dimerumic acid 11-mannoside/dimerumic acid
Terpene 1 6 21,484 squalestatin S1
1 8 22,538 –
1 9 21,569 –
Fungal-RiPP precursor synthase-like 1 8 60,975 –
Betalactone synthase 1 6 23,512 –
1 8 30,837 –
Isocyanide synthase 1 9 42,389 –
Total 33 – – –

Notes.

NRPS
Non-ribosomal peptide synthetase
T1PKS
type 1 Polyketide synthase
RiPP
Ribosomally synthesized and post-translationally modified peptide