Table.

Adjusted odds ratios for the impact of platelets and other clinically relevant covariates on 30-day mortality in patients with bloodstream infection.

	Houston Methodist Cohort	MIMIC-IV Cohort
Variable	aOR (95% CI)
Platelet strata (k/μL)
< 50	4.66 (3.91–5.55)	4.28 (2.97–6.17)
50–99	2.61 (2.25–3.02)	2.27 (1.66–3.12)
100–149	1.55 (1.37–1.76)	1.39 (1.02–1.89)
≥ 150	Referent	Referent
Age (per year)	1.02 (1.02–1.02)	1.03 (1.02–1.03)
Female gender	0.99 (0.90–1.08)	1.03 (0.82–1.28)
Race
Black	1.09 (0.97–1.23)	0.96 (0.65–1.40)
Asian	1.13 (0.92–1.39)	1.14 (0.62–2.08)
Other/unk.	1.44 (1.15–1.80)	1.88 (1.43–2.47)
White	Referent	Referent
ECI (per point increase)	1.05 (1.04–1.06)	1.08 (1.04–1.12)
Vasopressors	2.90 (2.33–3.64)	2.89 (1.97–4.24)
Any RRT	1.06 (0.92–1.23)	1.31 (0.93–1.85)
Increasing oxygen modality	1.56 (1.52–1.59)	1.43 (1.34–1.53)
WBC (per k/μL increase)	1.01 (1.01–1.02)	1.03 (1.01–1.04)

Abbreviations: CI, confidence interval; ECI, Elixhauser comorbidity index; OR, odds ratio; RRT, renal replacement therapy; unk., unknown; WBC, white blood cell.