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. Author manuscript; available in PMC: 2026 Apr 17.
Published before final editing as: J Comput Graph Stat. 2025 Apr 17:10.1080/10618600.2025.2461222. doi: 10.1080/10618600.2025.2461222

Table 3:

The p-values, warning accuracy, and sensitivity weights for the two binary outcomes of interest in the PCPT under Fisher’s sharp null and significance level α = 0.05.

Outcome Prostate Cancer High-Grade Prostate Cancer
(Sample Size N) (N=9060) (N=9037)
Relative Risk 0.75 (Protective Factor) 1.27 (Risk Factor)
p-value 4.66 ×10−13 6.79 ×10−3
Reject H0sharp or Not Yes Yes
Causal Conclusion Prevents Prostate Cancer Promotes High-Grade Cancer
Warning Accuracy 98.37% 99.88%
Minimal Alteration # 147 11
Sensitivity Weights False Positives False Negatives False Positives False Negatives
Finasteride 0 132/147 2/11 0
Placebo 15/147 0 0 9/11