Table 3:
The p-values, warning accuracy, and sensitivity weights for the two binary outcomes of interest in the PCPT under Fisher’s sharp null and significance level α = 0.05.
| Outcome | Prostate Cancer | High-Grade Prostate Cancer | ||
|---|---|---|---|---|
| (Sample Size N) | ||||
| Relative Risk | 0.75 (Protective Factor) | 1.27 (Risk Factor) | ||
| p-value | 4.66 ×10−13 | 6.79 ×10−3 | ||
| Reject or Not | Yes | Yes | ||
| Causal Conclusion | Prevents Prostate Cancer | Promotes High-Grade Cancer | ||
| Warning Accuracy | 98.37% | 99.88% | ||
| Minimal Alteration # | 147 | 11 | ||
| Sensitivity Weights | False Positives | False Negatives | False Positives | False Negatives |
| Finasteride | 0 | 132/147 | 2/11 | 0 |
| Placebo | 15/147 | 0 | 0 | 9/11 |