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. Author manuscript; available in PMC: 2025 Aug 26.
Published in final edited form as: Cereb Cortex. 2024 Jun 4;34(6):bhae224. doi: 10.1093/cercor/bhae224

Table 1.

Baseline characteristics of study participants.

All CHD (n=247) SV (n=114) d-TGA (n=92) ToF (n=41) Non-CHD (n=94)
Variables
Mean (SD), Number (%), or Median [IQR]

Gestational age, weeks 39.3 (2.1) 38.8 (2.4) 39.9 (1.3) 39.4 (2.4) 39.6 (1.2)
Self-reported white race 221 (89) 107 (94) 81 (88) 33 (80) 75 (80)
Family social class 48.4 (12.9) 48.9 (13.8) 47.1 (12.5) 50.4 (10.9) 53.4 (9.9)
Genetic diagnosis 16 (6) 10 (9)† 0 6 (15)‡ -
Age at first operation, days 7 [4, 47] 6 [3, 27] 6 [4, 9] 163 [76, 337] -
DHCA duration, minutes 35 (25)* 39 (29)§ 36 (22) 26 (26)** -
Total support time, minutes 129 (40)* 125 (49)§ 142 (31) 96 (27)** -
Number of perioperative complications 1 [0, 2] 1 [0, 2] 1 [0, 2] 0 [0, 1] -
Any neurological event 51 (21) 26 (23) 20 (22) 5 (12) -
Number of catheterizations 2 [1, 4] 4 [3, 5] 1 [0, 1] 1 [0, 2] -
Number of operations 2 [1, 3] 3 [3, 3] 1 [1, 1] 1 [1, 2] -
Age at MRI, years 15.0 (2.2) 14.8 (3.0) 15.7 (0.8) 14.4 (1.0) 15.1 (1.9)

CHD: congenital heart disease, DHCA: deep hypothermic circulatory arrest, d-TGA: d-transposition of the great arteries, MRI: magnetic resonance imaging, SV: single ventricle, ToF: Tetralogy of Fallot

All variables are missing <3% unless otherwise noted.

*

Data is missing for 23 out of 247 participants (9%) and not relevant for 49 participants undergoing closed surgery.

†

Previously known genetic/phenotypic syndromes included VACTERL (n=1), VATER (n=1), 22q11 (n=1), CHARGE syndrome (n=1), Kartagener syndrome (n=1), Factor V Deficiency (n=1), Factor V Leiden Deficiency (n=1), Factor VII Deficiency (n=1), balanced translocation involving chromosomes 13 and 14 (n=1) and unspecified (n=1).

§

Data missing for 14 of 65 participants (22%) undergoing open surgery and not relevant for 49 participants undergoing closed surgery.

‡

Previously known genetic/phenotypic syndromes included 22q11 (n=1), VATER (n=2), VACTERL (n=2), and Alagille syndrome (n=1).

**

Data missing for 9 out of 41 participants (22%).