Table 1.
Participant Characteristics at Baseline, Overall and by Inflammation Status
| Characteristic* | All Participants n=1674 |
Low Inflammation n=877 |
High Inflammation n=797 |
|---|---|---|---|
|
| |||
| N (%) unless specified otherwise | |||
| Age (years), mean (SD) | 73.9 (2.8) | 73.9 (2.8) | 73.9 (2.8) |
| Female | 861 (51.4) | 432 (49.3) | 429 (53.8) |
| Black | 571 (34.1) | 273 (31.1) | 298 (37.4) |
| Highschool Education | 1335 (79.7) | 711 (81.1) | 624 (78.3) |
| Income above 50k/year | 271 (18.3) | 156 (20.3) | 115 (16.2) |
| Ever Smoker | 896 (53.5) | 445 (50.7) | 451 (56.6) |
| Alcohol use (> 1 drink/day) | 129 (7.7) | 60 (6.8) | 69 (8.7) |
| Sedentary (0 walking/week) | 672 (40.1) | 328 (37.4) | 344 (43.2) |
| Body Mass Index >= 30 | 407 (24.3) | 159 (18.1) | 248 (31.1) |
| Hypertension | 877 (52.4) | 401 (45.7) | 476 (59.7) |
| Cardiovascular disease | 338 (20.2) | 174 (19.8) | 164 (20.6) |
| Diabetes | 278 (16.6) | 110 (12.5) | 168 (21.1) |
| Stroke | 126 (7.5) | 51 (5.8) | 75 (9.4) |
| Depression | 63 (3.8) | 28 (3.2) | 35 (4.4) |
| Inflammatory Markers | |||
| C-Reactive Protein, μg/mL | 2.8 (4.3) | 1.4 (0.7) | 4.4 (5.8) |
| Interleukin-6, pg/mL | 2.3 (1.8) | 1.4 (0.6) | 3.2 (2.2) |
| Tumor Necrosis Factor-α, pg/mL | 3.4 (1.6) | 2.8 (0.7) | 4.1 (2.0) |
| Sensory impairment | |||
| One | 650 (38.8) | 321 (36.6) | 329 (41.3) |
| Multiple | 433 (25.9) | 206 (23.5) | 227 (28.5) |
| Multisensory impairment score, mean (SD) | 5.4 (2.5) | 5.2 (2.5) | 5.6 (2.5) |
Abbreviations: pg/mL, picogram per milliliter; SD, standard deviation; μg/mL, microgram per milliliter
*
Data collected at baseline except for sensory impairment measures (collected in years 3–5).