Table 4. Changes in cigarette smoking from baseline to week 8.
| Changes in cigarette smoking | Exclusive cigarette smokers (n=353) | Dual users (n=367) | ||
|---|---|---|---|---|
| Baseline | Week 8 | Baseline | Week 8 | |
| Characteristics of cigarette smoking at week 8 | ||||
| Frequency of cigarette smoking, mean (SD), [95% CI]a | ||||
| Average CPDb | 12.4 (7.1),11.6-13.1 | 9.3 (7.5), 8.5-10.1 | 10.7 (7.2), 10-11.5 | 8.3 (7.3), 7.5-9 |
| Absolute change from baseline | —c | –3.1 (4.5), –3.5 to 2.6 |
— |
–2.5 (4.4), –2.9 to –2 |
| Days without cigarette smoking among people who smoke daily | ||||
| n | 6 | 64 | 30 | 98 |
| Days per week, mean (SD), 95% CI | 1.5 (0.8), 0.6-2.4 | 3.8 (2.4), 3.2-4.4 | 2.2 (1.5), 1.6-2.8 | 3.6 (2.3), 3.2-4.1 |
| CPD reduction >50% from baseline, n (%) | ||||
| Reduced CPD >50% | — | 91 (25.8) | — | 103 (28.1) |
| Cigarette smoking by SPd variant used at week 8e | ||||
| Patterns of cigarette smoking by SP variant used, n (%)f | ||||
| Only SP tobacco variant (n=101/n=112) | ||||
| Daily user | 101 (100) | 86 (85.1) | 104 (92.9) | 92 (82.1) |
| Nondaily user | 0 (0) | 10 (9.9) | 8 (7.1) | 15 (13.4) |
| Nonuser | — | 5 (5) | — | 5 (4.5) |
| Only SP menthol variant (n=166/n=167) | ||||
| Daily smoker | 163 (98.2) | 135 (81.3) | 151 (90.4) | 124 (74.3) |
| Nondaily smoker | 3 (1.8) | 25 (15.1) | 16 (9.6) | 35 (21) |
| Nonsmoker | — | 6 (3.6) | — | 8 (4.8) |
| Both SP variants (n=37/n=59) | ||||
| Daily smoker | 37 (100) | 27 (73) | 56 (94.9) | 34 (57.6) |
| Nondaily smoker | 0 (0) | 9 (24.3) | 3 (5.1) | 20 (33.9) |
| Nonsmoker | — | 1 (2.7) | — | 5 (8.5) |
| Frequency of cigarette use (CPD) by SP variant used, mean (SD), 95% CIa | ||||
| Average CPD | ||||
| Only SP tobacco variant (n=101/n=112) | 13.4 (7.5), 12-14.9 |
10 (6.8), 8.7-11.4 |
12 (7.2), 10.7-13.4 |
9.7 (7.4), 8.3-11.1 |
| Absolute change from baseline | — | –3.4 (4.7), –4.3 to –2.5 |
— | –2.3 (4.8), –3.2 to –1.4 |
| Only SP menthol variant (n=166/n=167) | 12.1 (6.8), 11.1-13.1 |
8.7 (7.3), 7.6-9.9 |
10.4 (7.4), 9.3-11.5 |
7.7 (6.8), 6.7-8.8 |
| Absolute change from baseline | — | –3.4 (4.6), –4.1 to –2.6 |
— | –2.7 (4.4), –3.4 to –2 |
| Both SP variants (n=37/n=59) | 10.5 (5.8), 8.6-12.4 |
7.5 (6.9), 5.2-9.8 |
8.2 (5.2), 6.8-9.6 |
5.6 (5.5), 4.1-7 |
| Absolute change from baseline | — | –3 (3.8), –4.3 to –1.8 |
— | –2.6 (3.6), –3.5 to –1.7 |
| CPD reduction>50% from baseline by SP variant used, n (%) | ||||
| Reduced CPD>50% | ||||
| Only SP tobacco variant (n=101/N=112) | — | 18 (17.8) | — | 24 (21.4) |
| Only SP menthol variant (n=166/N=167) | — | 52 (31.3) | — | 48 (28.7) |
| Both SP variants (n=37/N=59) | — | 11 (29.7) | — | 23 (39) |
| Patterns of cigarette smoking, n (%)g | ||||
| Daily smoker | 347 (98.3) | 289 (81.9) | 337 (91.8) | 269 (73.3) |
| Nondaily smoker | 6 (1.7) | 49 (13.9) | 30 (8.2) | 77 (21) |
| Nonsmoker | — | 15 (4.2) | — |
21 (5.7) |
CPD calculated only among participants who smoked cigarettes at week 8.
CPD: cigarettes per day.
Not available.
SP: study product.
SP flavor variants used at week 8 were categorized as only tobacco SP variant, only menthol SP variant, or both SP variants.
Results for daily and nondaily smoking when stratified by SP flavor variants used may not equal the results for daily and nondaily smoking overall given some participants did not use the SP at week 8.
Daily cigarette smoking was an inclusion criterion for study enrollment and all (100%) participants in both study groups reported daily cigarette smoking. Results for the use pattern of cigarette smoking were based on data at baseline, during which some exclusive cigarette smokers (n=6) and dual users (n=30) did not smoke daily.