Table 4.
Genes housing cancer related mirtrons are grouped by functional categories defined by high-level GO terms.
| N | High Level GO Category | Genes |
|---|---|---|
| 11 | GO:0006950 response to stress | SCRIB LRP1 RPS6KA1 ABCF1 |
| 11 | GO:0009893 positive regulation of metabolic process | RPS6KA1 ABCF1 SCRIB LRP1 |
| 4 | GO:0009056 catabolic process | LRP1 SHMT1 PISD |
| 4 | GO:0009653 anatomical structure morphogenesis | SCRIB RPS6KA1 LRP1 |
| 4 | GO:0042221 response to chemical | SHMT1 SCRIB LRP1 |
| 4 | GO:0044085 cellular component biogenesis | SHMT1 NOP56 DHX30 |
| 4 | GO:0065009 regulation of molecular function | LRP1 RPS6KA1 SCRIB |
| 3 | GO:0008283 cell population proliferation | SCRIB RPS6KA1 |
| 3 | GO:0009719 response to endogenous stimulus | SHMT1 LRP1 |
| 2 | GO:0002376 immune system process | SCRIB LRP1 |
| 2 | GO:0040007 growth | RPS6KA1 |
| 2 | GO:0040011 locomotion | SCRIB LRP1 |
| 2 | GO:0016049 cell growth | RPS6KA1 |
| 2 | GO:0023051 regulation of signaling | SCRIB LRP1 |
| 2 | GO:0032879 regulation of localization | SCRIB LRP1 |
| 2 | GO:0033036 macromolecule localization | SCRIB LRP1 |
| 2 | GO:0040008 regulation of growth | RPS6KA1 |
| 2 | GO:0048870 cell motility | SCRIB LRP1 |
| 2 | GO:0050793 regulation of developmental process | RPS6KA1 |
| 2 | GO:0051094 positive regulation of developmental process | RPS6KA1 |
| 2 | GO:0051234 establishment of localization | LRP1 SCRIB |
| 2 | GO:0051239 regulation of multicellular organismal process | SCRIB LRP1 |
| 2 | GO:0051240 positive regulation of multicellular organismal process | SCRIB LRP1 |
| 2 | GO:0051641 cellular localization | SCRIB LRP1 |
| 2 | GO:0051674 localization of cell | SCRIB LRP1 |
| 1 | GO:0000003 reproduction | PHC2 |
| 1 | GO:0022414 reproductive process | PHC2 |
| 1 | GO:0002252 immune effector process | LRP1 |
| 1 | GO:0002682 regulation of immune system process | SCRIB |
| 1 | GO:0002683 negative regulation of immune system process | SCRIB |
| 1 | GO:0003006 developmental process involved in reproduction | PHC2 |
| 1 | GO:0003008 system process | LRP1 |
| 1 | GO:0006955 immune response | LRP1 |
| 1 | GO:0007155 cell adhesion | SCRIB |
| 1 | GO:0009605 response to external stimulus | SCRIB |
| 1 | GO:0016080 synaptic vesicle targeting | SCRIB |
| 1 | GO:0019953 sexual reproduction | PHC2 |
| 1 | GO:0023057 negative regulation of signaling | LRP1 |
| 1 | GO:0030155 regulation of cell adhesion | SCRIB |
| 1 | GO:0032504 multicellular organism reproduction | PHC2 |
| 1 | GO:0040012 regulation of locomotion | LRP1 |
| 1 | GO:0040013 negative regulation of locomotion | LRP1 |
| 1 | GO:0042330 taxis | SCRIB |
| 1 | GO:0045321 leukocyte activation | SCRIB |
| 1 | GO:0048583 regulation of response to stimulus | LRP1 |
| 1 | GO:0048609 multicellular organismal reproductive process | PHC2 |
| 1 | GO:0048646 anatomical structure formation involved in morphogenesis | SCRIB |
| 1 | GO:0065008 regulation of biological quality | SCRIB |