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. Author manuscript; available in PMC: 2026 Feb 23.
Published in final edited form as: J Cell Sci. 2025 Jul 31;138(20):jcs264133. doi: 10.1242/jcs.264133

Figure 2.

Figure 2

Attenuated Hedgehog signaling through Gli1 inactivation increases cystic severity in Pkd1RC/RC mice. (A) KW/BW ratio and (B) CV % of 90-day Pkd1RC/RC mouse kidneys with and without Gli1 expression. Comparison of the datasets were done using the Mann-Whitney test and presented as mean ± standard error of mean (SEM). ***P=0.0001; ****P<0.0001.