Table 3. Prediction of the deleterious effects of nonsynonymous single-nucleotide polymorphisms related to SARS-CoV-2 using SIFTa and PolyPhen.
| Variant ID | Amino acid mutation | SIFT score | SIFT class | PolyPhen score | PolyPhen class |
|---|---|---|---|---|---|
| rs765452935 | Q658H | 0.01 | Deleterious | 0.003 | Benign |
| rs144657795 | D657G | 0 | Deleterious | 0.097 | Benign |
| rs758594009 | D654N | 0 | Deleterious | 0.063 | Benign |
| rs780262610 | F652L | 0.81 | Tolerated | 0.015 | Benign |
SIFT: Sorting Intolerant From Tolerant.