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. 2025 Jul 26;17(7):e88821. doi: 10.7759/cureus.88821

Table 2. Comparative outcomes of upper-tract recurrence following radical cystectomy.

GC: Gemcitabine-cisplatin; DFS: Disease-free survival; NED: No evidence of disease; UTUC: Upper-tract urothelial carcinoma

Study Age/Sex Anastomosis Presentation Management Outcome
Current Case 48 / M Bricker → Wallace (revised) Isolated conduit hematuria Laparoscopic nephroureterectomy + adjuvant GC NED at 18 months
Stemrich et al. [11] 58 / M Wallace Hematuria + hydronephrosis Robot-assisted nephroureterectomy + conduit revision NED at 24 months
Ślusarczyk et al. [19] 62 / F Bricker Incidental CT lesion Open salvage surgery Local recurrence at 12 months
Birtle et al. [14] Cohort (n = 261) Mixed Symptomatic/asymptomatic Adjuvant GC vs surveillance 55% DFS benefit with GC
Krafft et al. [16] Cohort (n = 178) Bricker / Wallace Anastomotic UTUC Nephroureterectomy ± adjuvant therapy Recurrence unrelated to anastomosis