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. 2025 Mar 3;20(4):248–255. doi: 10.1159/000544967

Table 2.

Treatment algorithm based on the IGM-TCC

Initial treatment option Alternative treatment option1
Pregnancy/lactation OBS ILS/TOPS
Type 1 disease OBS ILS/TOPS
Type 2 disease ILS/TOPS2
Type 3 disease SS IMT/COMB
Type 4 disease
 Resistant IMT COMB
 Recurrent According to reclassification
Follow-up During treatment, follow-up should be scheduled every month
Decision to discontinue treatment When a CCR is achieved in both physical examinations and radiological assessments

In all types, abscesses should be drained: deep abscesses under ultrasound guidance and superficial abscesses via skin incisions.

OBS, observation – regular monitoring without active intervention, except for drainage when necessary; ILS, intralesional steroid – steroid injection administered directly into the lesion; TOPS, topical steroid – steroid applied to the skin surface; SS, systemic steroids – steroids taken orally or intravenously; IMT, immunosuppressive therapy – treatment that suppresses immune system activity (e.g., methotrexate, azathioprine); COMB, combination therapy – use of multiple treatment modalities together (e.g., SS + SURG/IMT/TOPS/ILS/ABX, IMT + SURG, etc.); CCR, complete clinical response.

Consensus is indicated in bold text.

1If necessary, this may be considered a subsequent or additional treatment to the initial therapy.

2In our study, the consensus threshold was set at 80%; however, since a high level of agreement was achieved in the 70–80% range, it was recommended as the first-line treatment for Type 2 disease.