Table 2.
Multivariable logistic regression analysis results of factors associated with positive margins after BCS in 423 cases with breast cancer or carcinoma in situ
| Variable | Adjusted OR | 95% CI | p value |
|---|---|---|---|
| Age at time of surgery (years) | 1.01 | 0.97–1.05 | 0.685 |
| Cup size | |||
| A–B | 0.85 | 0.22–3.19 | 0.804 |
| C–D | 0.97 | 0.31–3.02 | 0.958 |
| >E | 1 (reference) | ||
| Node status | |||
| Positive | 1.13 | 0.27–4.77 | 0.865 |
| Negative | 1 (reference) | ||
| Invasive lobular carcinoma | |||
| Yes | 4.97 | 1.91–12.94 | 0.001 |
| No | 1 (reference) | ||
| Radiological underestimation (mm) | 0.99 | 0.95–1.04 | 0.663 |
| Lumpectomy size (mm) | 0.97 | 0.94–1.00 | 0.022 |
| Postoperative pathological tumor size (mm) | 1.07 | 1.03–1.11 | 0.001 |
| Hospital type | |||
| Low-volume | 3.90 | 1.58–9.66 | 0.003 |
| High-volume | 1 (reference) | ||
In this multivariable logistic regression model, all variables were adjusted for all other variables except for the one of interest.
BCS, breast-conserving surgery; OR, odds ratio; CI, confidence interval.