Fig. 2. Pathological findings of resected specimen in Case 1 (A, B) Macroscopically, a 5 mm white-colored area localized to the main pancreatic duct 15 mm from the pancreatic margin. Distally, the main pancreatic duct was dilated, and pancreatic parenchyma appeared atrophic. (C, D) No residual cancer was observed in the white-colored area surrounding the main pancreatic duct, confirming diagnosis of pathological complete response. (Hematoxylin and eosin staining, ×12.5; C) (Hematoxylin and eosin staining, ×100; D).