Table 3. Results from the external exposome-wide association study (ExWAS) in phase 1.
| Exposure variable | Category | Transformation | Phase 1, discovery set | Phase 1, replication set | Phase 2 | |||
|---|---|---|---|---|---|---|---|---|
| ORa (95% CI) | q-value | ORa (95% CI) | q-value | ORa (95% CI) | q-value | |||
| Monthly (May) maximum temperature (°F) | Neighborhood and built environment | No transform | 1.06 (1.03-1.10) | 2.94E-03 | 1.04 (1.02-1.06) | 3.67E-05 | 1.04 (1.02-1.06) | 6.57E-05 |
| Median income of grandparent householder and/or spouse responsible for grandchildren <18 years (US dollars, inflation-adjusted to data file year) | Economic stability | sqrt_x | 0.95 (0.92-0.98) | 3.86E-02 | 0.96 (0.94-0.98) | 5.42E-03 | 0.98 (0.96-1.00) | 7.64E-02 |
| Percentage of households not receiving food stamps/SNAPb with income below the poverty level | Economic stability | Yeo-Johnson | 1.05 (1.02-1.07) | 4.77E-02 | 1.05 (1.03-1.07) | 3.67E-05 | 1.02 (1.00-1.04) | 8.84E-02 |
a
OR: odds ratio.
b
SNAP: Supplemental Nutrition Assistance Program.