Table 2:
PH Screening outcomes
| PH Screening | All Infants Pre-Screen (n=513) | All Infants Post-Screen (n=544) | p-value | Risk+ Pre-Screen (n=270) | Risk+ Post-Screen (n=273) | p-value | PH+ Pre-Screen (n=59) | PH+ Post-Screen (n=90) | p-value |
|---|---|---|---|---|---|---|---|---|---|
| Meets criteria based on BW <750g and mechanical ventilation at 28 days | 64 (12.5%) | 62 (11.4%) | 0.64 | ||||||
| Meets criteria based on risk factors | 119 (23.2%) | 143 (26.3%) | 0.25 | ||||||
| Meets criteria for prolonged respiratory support: | |||||||||
| HFNC | 106 (20.7%) | 120 (22.1%) | 0.60 | ||||||
| CPAP | 35 (6.8%) | 43 (7.9%) | 0.56 | ||||||
| NIPPV | 145 (28.3%) | 106 (19.5%) | < 0.001** | ||||||
| Last FiO2 > 30 | 140 (27.3%) | 178 (32.8%) | 0.06 | ||||||
| Grade 2–3 BPD | 67 (13.1%) | 70 (12.9%) | 0.92 | ||||||
| Meets criteria for screening | 270 (52.6%) | 273 (50.2%) | 0.46 | 56 (94.9%) | 83 (92.2%) | 0.74 | |||
| ≥ 1 echo at day of life ≥ 28 | 179 (34.9%) | 255 (46.9%) | <0.001** | 144 (53.3%) | 196 (71.8%) | <0.001** | |||
| PH+ on ≥ 1 echo ≥ day of life 28 | 59 (11.5%) | 90 (16.5%) | 0.02** | 56 (20.7%) | 83 (30.4%) | 0.01** | |||
| DOL of 1st PH + echo ≥ DOL 28 | 73 (28–193) | 55 (28–212) | 0.01 |
Data presented as n(%), median (range). HFNC – High Flow Nasal Cannula ≥ 2 LPM, CPAP – Continuous Positive Airway Pressure, NIPPV – Nasal Intermittent Positive Pressure Ventilation