Table 5:

3-Year Outcomes

Outcome	Surgery + CRT (n = 12,493)	CRT (n = 19,874)	Comparison of Proportions (%)
OS, Advanced-Stage	79.2% (95% CI 59.8%−93.4%)	70.2% (95% CI 57.1%−81.8%)	9.0 (95% CI 8.0%−10.0%, p < 0.0001)
OS, HPV-Positive	93.4% (95% CI 90.6%−95.7%)	88.5% (95% CI 83.4%−92.8%)	4.9 (95% CI 3.5%−6.3%, p < 0.0001)
OS, HPV-Negative	80.5% (95% CI 77.5%−83.3%)	65.0% (95% CI 62.6%−67.4%)	15.5 (95% CI 11.7%−19.1%, p < 0.0001)
DSS, Advanced-Stage	89.7% (95% CI 72.2%−99.0%)	81.1% (95% CI 58.7%−96.0%)	8.6 (95% CI 7.8%−9.4%, p < 0.0001)
RFS, Advanced-Stage	78.6% (95% CI 53.8%−95.5%)	61.2% (95% CI 33.9%−85.2%)	17.4 (95% CI 16.4%−18.4%, p < 0.0001)

OS = Overall Survival, DSS = Disease-Specific Survival, RFS = Recurrence-Free Survival