Table 6:

5-Year Outcomes

Outcome	Surgery + CRT (n = 12,493)	CRT (n = 19,874)	Surgery + Radiation (n = 1,029)	Comparison of Proportions (%)
OS, Advanced-Stage	67.1% (95% CI 55.6%−77.6%)	53.9% (95% CI 37.7%−69.7%)	63.1% (95% CI 31.9%−89.2%)	13.2 (95% CI 12.1%−14.3%, p < 0.0001)*; 4.0 (95% CI –0.6%−8.8%, p = 0.0863)^; 9.2 (95% CI 4.4%−13.7%, p = 0.0002)~
DSS, Advanced-Stage	77.5% (95% CI 66.2%−87.1%)	63.5% (95% CI 49.1%−76.7%)	55.9% (95% CI 49.1%−62.5%)	14.0 (95% CI 13.0%−15.0%, p < 0.0001)*; 21.6 (95% CI 16.9%−26.4%, p < 0.0001)^; 7.6 (95% CI −16.8%−26.9%, p = 0.5480)~
DFS, Advanced-Stage	58.6% (95% CI 50.8%−66.1%)	39.7% (95% CI 2.1%−87.8%)	-	18.9 (95% CI 17.8%−20.0%, p < 0.0001)*
RFS, Advanced-Stage	70.9% (95% CI 49.1%−88.6%)	69.1% (95% CI 42.0%−90.4%)	71.9% (95% CI 35.2%−96.7%)	1.8% (95% CI 0.7%−2.9%, p = 0.0019)*; 1.0 (95% CI-3.5%−5.2%, p = 0.6568)^; 2.8 (95% CI –1.7%−6.9%, p = 0.2177)~

OS = Overall Survival, DSS = Disease-Specific Survival, DFS = Disease-Free Survival, RFS = Recurrence-Free Survival

-Data not provided in text.

^*Comparing Surg + CRT and CRT,

^{^}Comparing Surg + CRT vs Surg + Radiation, ~Comparing CRT and Surg + Radiation