. Author manuscript; available in PMC: 2026 Apr 19.

Published in final edited form as: Head Neck. 2025 Apr 19;47(9):2486–2498. doi: 10.1002/hed.28167

Table 7:

Loco- and Locoregional Control Outcomes

	Surgery + CRT (n = 12,493)	CRT (n = 19,874)	Surgery + Radiation (n = 1,029)	Comparison of Proportions (%)
LC, Advanced Stage	81.1% (95% CI 44.0%−99.7%)	80.4% (95% CI 73.0%−86.6%)	71.7% (95% CI 24.6%−99.5%)	0.7 (95% CI −0.2%−1.6%, p = 0.1205)^*; 9.4 (95% CI5.2%−13.9%, p < 0.0001)^{^}; 8.7 (95% CI 4.6%−13.2%, p < 0.0001)~
LRC, Advanced Stage	78.2% (95% CI 64.6%−89.3%)	85.7% (95% CI 78.4%−91.3%)	80.9% (95% CI 63.9%−93.4%)	7.5 (95% CI 6.6%−8.4%, p < 0.0001)^*; 2.8 (95% CI –1.4%−6.2%, p = 0.1863)^{^}; 4.8 (95% CI 1.3%−8.8%, p = 0.0055)

LC = Local Control, LRC = Locoregional Control

Comparing Surg + CRT and CRT

^{^}

Comparing Surg + CRT vs Surg + Radiation, ~Comparing CRT and Surg + Radiation