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. 2025 Aug 22;105(6):e213836. doi: 10.1212/WNL.0000000000213836

Table 3.

Logistic Regression of Incidence of Participants With Alzheimer Disease-Related Pathology Against MRI Cerebral Small Vessel Disease Markers (EPVS, White Matter Hyperintensities, Lacunes, Microbleeds) in the Mild Cognitive Impairment Cohort

Variable OR 95% CI p Value
Age 1.041 1.010–1.074 0.009a
APOE ε4 carrier status 2.456 1.305–4.623 0.005a
EPVS Staals score 1.877 1.045–3.370 0.035a

Abbreviations: OR = odds ratio; EPVS = enlarged perivascular spaces.

a

Significance level set at p < 0.05. Age, APOE ε4 status and PVS Staals score were included in the model; all other factors were not retained.