Fig. 1. A scatter plot and partial regression plots between white matter hyperintensities volume and gait speed. (A) Negative association between WMH volume and gait speed in both groups. (B) Negative significant association (β = −1.010, P < 0.001) between WMH volume and gait speed in MCI group with MCRS after adjusting for age, education, gender, KGDS, hippocampal volume, grip strength, CCI, eICV, and the presence of APOE ε4. (C) Negative significant association (β = −0.427, P = 0.016) between WMH volume and gait speed in MCI group without slow gait after adjusting for age, education, gender, KGDS, hippocampal volume, grip strength, CCI, eICV, and the presence of APOE ε4.

MCRS = motoric cognitive risk syndrome, MCI = mild cognitive impairment, WMH = white matter hyperintensities, eICV = estimated intracranial volume, APOE ε4 = apolipoprotein E ε4 allele, CCI = Charlson comorbidity index, KGDS = Korean version of geriatric depression scale.