Table 1. Demographic and clinical characteristics of all participants.
| Variables | MCI with motoric cognitive risk syndrome (n = 31) | MCI without slow gait (n = 50) | P value | |
|---|---|---|---|---|
| Age, yr | 77.7 ± 4.7 | 73.1 ± 4.4 | < 0.001 | |
| Female, % | 14 (43.8) | 28 (57.1) | 0.739 | |
| Education, yr | 9.8 ± 5.2 | 9.2 ± 4.6 | 0.568 | |
| Hypertension, % | 23 (71.9) | 29 (59.2) | 0.244 | |
| Diabetes, % | 5 (15.6) | 9 (18.4) | 0.750 | |
| APOE ε4 | 9 (29.0) | 17 (34.0) | 0.642 | |
| MMSE-KC | 23.5 ± 2.6 | 26.4 ± 2.0 | < 0.001 | |
| CDR-SOB | 0.7 ± 0.2 | 0.5 ± 0.2 | 0.001 | |
| KGDS | 12.8 ± 2.6 | 10.4 ± 4.4 | 0.008 | |
| CCI | 3.6 ± 1.0 | 3.4 ± 1.1 | 0.396 | |
| Brain volumes, mL | ||||
| eICV | 1,496.0 ± 148.1 | 1,530.6 ± 140.3 | 0.295 | |
| Hippocampus volume | 6.1 ± 0.6 | 6.4 ± 0.7 | 0.090 | |
| WMH volume | 13.9 ± 13.8 | 6.7 ± 4.3 | 0.001 | |
| Physical functions | ||||
| Body mass index, kg/m2 | 24.5 ± 2.6 | 25.0 ± 3.0 | 0.465 | |
| Gait speed, m/s | 0.75 ± 0.09 | 1.14 ± 0.17 | < 0.001 | |
| Grip strength, kg | 23.3 ± 7.1 | 25.3 ± 10.5 | 0.366 | |
Values are presented mean ± standard deviation or number (%).
MCI = mild cognitive impairment, APOE ε4 = apolipoprotein E ε4 allele, MMSE-KC = Korean version of mini-mental state examination, CDR-SOB = clinical dementia rating scale sum of boxes score, KGDS = Korean version of geriatric depression scale, CCI = Charlson comorbidity index, eICV = estimated intracranial volume, WMH = white matter hyperintensities.