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. 2025 Jul 3;40(33):e202. doi: 10.3346/jkms.2025.40.e202

Table 6. Univariate and multivariate logistic regression analysis of metabolic syndrome components affecting ocular hypertension.

Variables Univariate Multivariate
ORs (95% CI) P value ORs (95% CI) P value
Male 1.07 (0.40–2.85) 0.893 0.86 (0.36–2.06) 0.741
High blood pressure 1.29 (0.44–3.75) 0.644 0.98 (0.38–2.49) 0.963
High fasting glucose 1.72 (0.79–3.75) 0.169 1.18 (0.47–2.96) 0.724
High fasting insulin 2.02 (0.80–5.10) 0.136 1.13 (0.28–4.61) 0.865
High HOMA-IR 2.44 (1.08–5.48) 0.031* 2.23 (0.88–5.70) 0.092
High BMI 1.61 (0.64–4.05) 0.306 0.57 (0.28–1.16) 0.119
Abdominal obesity 2.38 (0.95–5.97) 0.065 2.90 (1.35–6.23) 0.007**
High triglyceride 1.03 (0.36–2.89) 0.962 0.76 (0.27–2.10) 0.592
Low HDL-C 0.61 (0.22–1.65) 0.326 0.41 (0.14–1.21) 0.106

Metabolic syndrome components; high blood pressure (systolic ≥ 130 mmHg or diastolic ≥ 85 mmHg); high fasting glucose (≥ 100 mg/dL); high fasting insulin (≥ 13 μIU/mL); high HOMA-IR (≥ 2.34); high BMI (≥ 25 kg/m2); abdominal obesity (male ≥ 90 cm, female ≥ 85 cm); high triglycerides (≥ 150 mg/dL); low HDL-C (male < 40 mg/dL, female < 50 mg/dL).

OR = odds ratio, CI = confidence interval, HOMA-IR = homeostasis model assessment of insulin resistance, BMI = body mass index, HDL-C = high-density lipoprotein cholesterol.

*P < 0.05 and **P < 0.01 were considered statistically significant.