Table 2.

Correlations between intestinal microbiota, metabolic characteristics, and metabolites.

Intestinal microbiota	Metabolic characteristics	Correlations with liver metabolites	Significance
Firmicutes	Promotes energy absorption → Heat accumulation → Obesity	Significant positive correlation with LysoPC (15:5/0:0), LysoPC(18:1(11Z)/0:0), PC(18:1(6Z)/0:0)	p < 0.05
Bacteroidetes	Degrades polysaccharides and regulates host metabolism	Significant negative correlation with, LysoPC(22:5(4Z, 7Z, 10Z, 13Z, 16Z)/0:0), LysoPC (18:1(11Z)/0:0), LysoPC (20:4(5Z, 8Z, 11Z, 14Z)/0:0), LysoPC (16:1(9Z)/0:0)	p < 0.05
Allobaculum	Lactic acid-producing pathogenic bacteria; significantly enriched in high-fat diet (HFD)	significant positive correlation with LysoPC (16:1(9Z)/0:0), LysoPC (18:1(11Z)/0:0), PC (18:1(6Z)/0:0)	p < 0.05
Faecalibaculum	Pro-inflammatory bacteria → Damages intestinal barrier and exacerbates hepatic steatosis	significant positive correlation with PC (18:3/18:1), LysoPC (22:5(4Z, 7Z, 10Z, 13Z, 16Z)/0:0, LysoPC (15:0/0:0)	p < 0.05