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. 2025 Aug 12;12:1575580. doi: 10.3389/fnut.2025.1575580

Table 3.

Exercise protocols used in the studies.

Author and Year Type of exercise Intensity Volume Exercise session Frequency and period Supervised or non-supervised
Balachandran
2014 (26)
Hypertrophy/strength 70% of 1-RM 110–120 min/week The subject performed 10 repetitions. 1-RM was reached by all subjects in no more than 4–5 attempts. 2 day/w, 15 weeks Supervised
High-speed circuit 50–80% of 1-RM 80–90 min/week Leg press, chest press, lat pulldown, biceps curl, leg curl, hip adduction, calf raise, shoulder press, and hip adduction.
Kim
2016 (28)
CE NA 180 min/week Warm-up, weight/machine training, stationary bicycle AR, and chair/standing exercise. 3 day/w, 12 weeks Supervised
Maltais
2016 (27)
RT 80% of 1-RM 180 min/week Shoulder press, sit-ups, biceps curls, leg press, bench press, leg extension, rowing extensions, and leg curls (3 sets × 8 repetitions). 3 day/w, 16 weeks NA
Vasconcelos 2016 (29) RT 40–75% of 1-RM 120 min/week Straight leg raises for posterior leg muscles, straight leg raise, straight leg raises with crossing. 2 day/w, 10 weeks Supervised
Chen
2017 (31)
RT 60–70% of 1-RM 120 min/week Shoulder presses, bicep curls, triceps curls, bench presses, deadlifts, leg swings, squats, standing rows, unilateral rows, and split front squats (3 sets × 8–12 repetitions). 2 day/w, 8 weeks Supervised
AR Stepping on the spot, knee lifts, high knee running, rowing arm swings, arm swings, twist steps, arm raises, squats, V steps, mambo steps, diamond steps, and point step jumps.
CE The subject performed once a week with the AR following 48 h after RT.
Huang
2017 (32)
ERT 13 points on the RPE 165 min/week 3 sets of 10 repetitions for training the shoulders, arms, lower limbs, chest, and abdomen. 3 day/w, 12 weeks Supervised
Liao
2017 (24)
RT 13 points on the RPE 135–150 min/week 3 sets of 10 gentle concentric and eccentric contractions are slowly performed through the full range of motion. 3 day/w, 12 weeks Supervised
Park
2017 (33)
CE RPE in the 13–17 range 150–240 min/week RT included elbow flexion, wrist flexion, shoulder flexion, lateral raise, front raise, chest press, reverse flies, side bend, dead lift, squat, leg press, and ankle plantar flexion. AR involved various walking activities (sideways, backward, and forward walking, and slow and fast indoor walking). 3 day/w, 24 weeks Supervised
Chiu
2018 (39)
RT 12–13 points of RPE 120 min/week Upper body exercises included 3 sets of training that targeted the biceps, deltoids, grip, and pinch.
Lower extremities included 3 sets of leg extensions, leg flexions, calf raises, stepping forward and sideward, and others.
2 day/w, 12 weeks Supervised
Liao
2018 (37)
ERT 13 points on the RPE scale 165 min/week Seated chest press, seated row, seated shoulder press, knee extension, knee flexion, hip flexion, and hip extension. 3 day/w, 12 weeks Supervised
Nabuco
2019 (30)
RT Increases from 2 to 5% of 1-RM for upper limb and 5 to 10% for lower limb NA Chest press, horizontal leg press, seated row, knee extension, preacher curl (free weights), leg curl, triceps pushdown, and seated calf raise. 3 day/w, 12 weeks Supervised
Liao
2020 (38)
ERT 65–80% of 1-RM; 13–15 points of RPE 110 min/week Seated chest press, seated row, seated shoulder press, knee extension, knee flexion, hip flexion, and hip extension. 2 day/w, 12 weeks Supervised
Jung
2022 (34)
Circuit
exercise
60–80% of HRR 75–225 min/week Walking in place, shoulder press and squat, twist to dash, lunge, jumping jacks, kickback, push-up, crunch, hip bridge, and bird dog. 3 day/w, 12 weeks Supervised
Magtouf
2023 (36)
Concurrent
exercise
300 a.u. 120 min/week Motor skill exercises (zigzag cone walking, obstacle course walk, ladder agility drills, direction change walking, obstacle relay race, zigzag ball passing, balance board zigzag walk, and cone weaving);
Strengthening exercises (calf raises, toe taps, seated leg extensions, mini squats, seated leg lifts, bridge exercise, leg raises, hip abduction with resistance band);
Posture exercises (single-leg balance with eyes closed, heel-to-toe walking with eyes closed, balance board or wobble board, tandem stance, toe tapping, ball toss, reaching and bending, sensory walk, picking up objects with toes).
2 day/w, 24 weeks Supervised
Jung
2024 (35)
Circuit exercise 60–85% of HRR 135–225 min/week Walking in place, shoulder presses and squats, twist dashes, lunges, jumping jacks, kickbacks, modified push-ups, crunches, hip bridges, and bird dogs. 3 day/w, 12 weeks Supervised

ERT, elastic resistance training; RT, resistance training; AR, aerobic exercise; CE, combined exercise, a mix of RT and AR; 1-RM, one repetition maximum; HRmax, heart rate maximum; RPE, rating of perceived exertion; HRR, heart rate reserve; a.u., arbitrary units; NA, not available.