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. 2025 Aug 12;16:1627337. doi: 10.3389/fendo.2025.1627337

Table 4.

The relationship between AIP and the progression from normoglycemia to pre-DM in different competing risk models.

Exposure Crude model (SHR, 95% CI, P) Model I (SHR, 95% CI, P) Model II (SHR, 95% CI, P)
AIP (per 0.1 unit) 1.21 (1.16, 1.25) < 0.001 1.12 (1.08, 1.17) < 0.001 1.09 (1.04, 1.14) < 0.001
AIP quartiles
Q1 Ref. Ref. Ref.
Q2 2.38 (1.48, 3.84) < 0.001 1.75 (1.08, 2.83) 0.023 1.61 (0.99, 2.61) 0.055
Q3 4.16 (2.67, 6.50) < 0.001 2.53 (1.60, 4.00) < 0.001 2.18 (1.37, 3.47) 0.001
Q4 5.91 (3.83, 9.10) < 0.001 3.01 (1.92, 4.74) < 0.001 2.29 (1.44, 3.65) < 0.001
P for trend <0.001 <0.001 <0.001

Crude Model: We did not adjust other covariates.

Model I: We adjust sex and age.

Model II: We adjust sex, drinking status, BMI, age, Hs-CRP, ALT, SBP, physical activity, smoking status, Scr, GGT, LDL-c, AST, hypertension, DLP-MED, and HTN-MED.

SHR, sub-distribution hazard ratio; Ref, reference; CI, confidence interval.