TABLE 1.

Schedule of enrollment, intervention and assessment.

Time point	Enrollment Week -1	Allocation Week 0	Treatment phase Week 1-2	Follow-up Week 3	Follow-up Week 10
Assessment of eligibility
Eligible screen	X	–	–	–	–
Informed consent	X	–	–	–	–
Randomization
Allocation	–	X	–	–	–
Intervention
Conventional treatment	–	–	X	–	–
Heat-sensitive moxibustion plus conventional treatment	–	–	X	–	–
Primary outcome
The frequency of nocturia	–	X	–	X	X
Secondary outcomes
Pittsburgh sleepiness index (PSQI) scale	–	X	–	X	X
Nocturia on quality of life (N-QOL) questionnaire	–	X	–	X	X
Traditional Chinese medicine syndrome scoring scale	–	X	–	X	X
The level of arginine vasopressin (AVP)	–	X	–	X	X
The level of atrial natriuretic peptide (ANP)	–	X	–	X	X