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. 2025 Aug 12;12:1592325. doi: 10.3389/fmed.2025.1592325

Table 2.

Clinical characteristics according to prognosis in the two cohorts.

Variables Death p value
No (n = 697) Yes (n = 640)
Age, years 68 (56, 78) 74 (64, 82) < 0.0001
Sex, n (%)
Male 504 (72.3%) 464 (72.5%) 0.006
Female 193 (27.7%) 176 (27.5%)
Smoke 307 (44.0%) 314 (49.1%) 0.066
Drink 234 (33.6%) 207 (32.3) 0.633
SOFA score 5 (3, 7) 7 (4, 9) < 0.0001
APACHE II score 16 (11, 21) 19 (15, 24) < 0.0001
Respiratory rate, cycles/min 23 (20, 29) 23 (20, 28) 0.302
Systolic blood pressure, mm Hg 118 (100, 148.5) 123 (107, 138.7) 0.086
Diastolic blood pressure, mm Hg 69 (58, 80.5) 70 (61, 80) 0.169
P/F, mm Hg 207 (155.7, 267.3) 173.7 (116.4, 235.1) < 0.0001
WBC count, ×109/L 10.2 (7.0, 13.8) 12.6 (8.8, 17.4) < 0.0001
LYM count, ×109/L 0.83 (0.6, 1.2) 0.7 (0.4, 1.1) < 0.0001
N/L 9.3 (5.6–17.2) 14.3 (7.6–24.6) < 0.0001
HgB, g/L 105 (88, 121.5) 105 (89, 123) 0.492
Platelet count, ×109/L 201 (136.5, 287) 177 (113, 251.8) < 0.0001
TP, g/L 56.3 (51.8, 61.0) 56.0 (50.2, 60.6) 0.111
ALB, g/L 29.9 (27.2, 33.1) 28.8 (25.8, 32.2) < 0.0001
LDH, U/L 298.5 (234, 424.8) 387 (268, 573) < 0.0001
CRE, μmol/L 56 (41, 82.5) 67 (48, 114) < 0.0001
BUN, mmol/L 8.2 (5.5, 12.6) 10.9 (7.0, 17.9) < 0.0001
CRP, mg/L 84.9 (40.9, 140.1) 107.1 (48.0, 172.8) < 0.0001
PCT 0.6 (0.2, 2.1) 1.2 (0.3, 4.9) < 0.0001
Glu, mmol/L 7.1 (5.8, 9.5) 7.3 (5.7, 9.8) 0.685
D-dimmer, μg/mL 2.4 (1.3, 4.8) 3.4 (1.7, 7.1) < 0.0001
Lac, mmol/L 1.4 (1.1, 1.9) 1.8 (1.4, 2.4) < 0.0001
VD 159 (22.8%) 410 (64.1%) < 0.0001