Table 3.

Association of laboratory values with 30-day all-cause mortality among patients with febrile neutropenia treated in the Northwest Ethiopia oncology centers

Laboratory tests (reference values)	Total (mean ± SD)	Mortality		P-value
		No (mean ± SD)	Yes (mean ± SD)
Hgb (12–16 g/dL)	12.3 ± 4.9	12.38 ± 5.4	12.1 ± 2.77	0.64
WBC (4.5–11 k/µL)	4.8 ± 2.6	5.995 ± 1.4	4.5 ± 2.3	0.22
PLT (150–450 k/µL)	269 ± 224	276 ± 237	243 ± 159	0.32
Lymphocytes (1–4.8 K/µL)	1.94 ± 1.2	2.1 ± 1.1	0.95 ± 0.3	0.0001*
CRP (0–0.5 mg/dL)	24.9 ± 8.6	22.7 ± 2.4	25.49 ± 1.8	0.43
ESR (2–30 mmh)	41.2 ± 3.5	40.47 ± 3.6	41.44 ± 2.9	0.079
eGFR (90–120 mL/min/1.73 m2)	93.6 ± 41.4	103.6 ± 42.4	89 ± 37.6	0.91
TP (6.4–8.3 g/dL)	6.1 ± 1.3	6.13 ± 1.28	6.3 ± 1.4	0.37
Albumin (3.5–5.5 g/dL)	4.1 ± 1.4	4.19 ± 1.3	2.8 ± 1.48	0.0014*
LDH (60–160 U/L)	896.38 ± 762.3	923.6 ± 143	792.1 ± 110	0.434
ALP (30–120 U/L)	79.1 ± 46.7	79.82 ± 45.8	76.35 ± 50.27	0.545
GGT (8–38 U/L)	39.4 ± 21.9	35.81 ± 21.5	53.2 ± 17.5	0.001*
AST (0–35 U/L)	35.5 ± 26.3	36.2 ± 26.1	32.8 ± 27	0.28
ALT 1 (0–40 U/L)	42.4 ± 34.5	41 ± 31.6	47.4 ± 43.8	0.13
Bil T (0.3–1.2 mg/dL)	1.17 ± 0.43	1.18 ± 0 .44	1.15 ± 0.43	0.58
Bil D (0.1–0.3 mg/dL)	0.81 ± 0.35	0.8 ± 0.36	0.82 ± 0.34	0.56
Na (135–145 mEq/L)	134.9 ± 8.86	135.1 ± 8 .8	134.4 ± 8.9	0.53
K (3.5–5 mEq/L)	3.89 ± 0.98	3.9 ± 0.99	3.76 ± 0 .97	0.15

ALT Alanine transferase, ALP alkaline phosphatase, AST aspartate transferase, Bil D bilirubin direct, Bil T bilirubin total, CRP C-reactive protein, eGFR estimated glomerular filtration rate, ESR erythrocyte sedimentation rate, GGT gamma-glutamyl transferase, Hgb hemoglobin, LDH lactate dehydrogenase, K potassium, Na sodium, PLT platelet count, SD standard deviation, TP total protein, WBC white blood cell count

*Significant association with 30-day all-cause mortality at P < 0.05