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. 2025 Aug 12;13:1595223. doi: 10.3389/fped.2025.1595223

Figure 2.

Three line graphs compare PT, APTT, and D-dimer levels over time (onset, 3 months, and 6 months) between VTE (red circles) and NO VTE (blue squares) groups. PT values show a slight increase over time in the VTE group and a decrease in the NO VTE group. APTT values fluctuate slightly in both groups with overlapping ranges. D-dimer levels rise over time in both groups, with VTE values consistently higher at 3 months but slightly lower than NO VTE at 6 months. Error bars indicate variability across all measures.

Temporal trends in coagulation parameters among glioma patients with and without VTE (n = 78, * indicates p < 0.05). This figure presents the Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), and D-dimer levels measured at disease onset (diagnosis) and at 3 and 6 months post-onset in patients with and without venous thromboembolism (VTE). The data indicate no significant differences in PT and APTT between the two groups. However, D-dimer levels increased over time in both groups, with no significant intergroup differences observed.