Skip to main content
. 2025 Aug 12;13:1595223. doi: 10.3389/fped.2025.1595223

Table 3.

Comparison of clinical information based on VTE occurrence.

Clinical information VTEa No VTEa p
Age (y) 10.01 ± 3.27 9.84 ± 3.91 0.62
Gender (female) 21 (33.33%) 60 (57.14%) <0.001
Anticoagulation therapy 2/34 (5.88%) 14 (18.92%) 0.14
Tumor volume (cm2) 34.54 ± 5.58 24.97 ± 9.02 <0.001
Tumor gradeb <0.001
3 6 (9.52%) 85 (80.95%)
4 57 (90.48%) 20 (19.05%)
Gene Expression
 IDH1 MUT 3 (6.52%) 17 (22.67%) <0.001
 ATRX + 5 (10.87%) 3 (4.00%) 0.27
 EGFR + 14 (30.43%) 15 (20.00%) 0.28
 MGMT Methylation 14 (30.43%) 25 (33.33%) 0.90
 p53 MUT 12 (26.09%) 11 (14.67%) 0.19
Treatment
 Radiotherapy 39 (65.00%) 80 (91.95%) <0.001
 Chemotherapy 18 (30.00%) 41 (48.24%) <0.001
 Target Therapies 4 (6.67%) 8 (9.20%) 0.78
 Chinese Traditional Medicine 5 (8.33%) 6 (6.90%) 0.77
Prolonged Bed Restc 45 (86.54%) 60 (98.36%) <0.001
Glucocorticoid Therapy 34 (56.67%) 30 (32.61%) <0.001
History of CVCP 2 (3.33%) 10 (11.63%) 0.14

VTE, venous thromboembolism; IDH MUT, isocitrate dehydrogenase mutation; ATRX +, alpha-thalassemia/mental retardation syndrome X-linked positive; EGFR +, epidermal growth factor receptor positive; MGMT, O6-methylguanine-DNA methyltransferase; p53, tumor protein p53; CVCP, central venous catheter placement.

a

Categorical variables are presented as percentages, while continuous variables are presented as mean ± standard deviation.

b

According to the retained pathological reports.

c

Bed rest for more than 2 weeks.