Table 1.
Amide exchange rates in Barnase (30 °C, pH 6.7). The residues listed are those for which confident rates were measured in both conditions
| Residue | Exchange rate (hr− 1), no betaine | Exchange rate (hr− 1), 1 M betaine |
|---|---|---|
| 11 | 0.057 | 0.0063 |
| 12 | 0.23 | 0.1 |
| 13 | 0.027 | 0.0047 |
| 14 | 0.0016 | 0.0015 |
| 15 | 0.0093 | 0.0056 |
| 17 | 0.18 | 0.0689 |
| 19 | 0.0024 | 0.0016 |
| 25 | 0.0016 | 0.0004 |
| 26 | 0.079 | 0.025 |
| 30 | 0.0026 | 0.0014 |
| 31 | 0.16 | 0.0304 |
| 33 | 0.032 | 0.0109 |
| 35 | 0.21 | 0.0751 |
| 45 | 0.33 | 0.0945 |
| 46 | 0.0078 | 0.0030 |
| 49 | 0.0052 | 0.0033 |
| 50 | 0.002 | 0.0016 |
| 51 | 0.0054 | 0.0027 |
| 56 | 0.0063 | 0.0020 |
| 75 | 0.0021 | 0.0003 |
| 76 | 0.0028 | 0.0015 |
| 87 | 0.047 | 0.016 |
| 88 | 0.0017 | 0.0015 |
| 89 | 0.0012 | 0.0017 |
| 95 | 0.028 | 0.0168 |
| 97 | 0.0016 | 0.0016 |
| 98 | 0.0041 | 0.0013 |
| 99 | 0.0056 | 0.0015 |