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. 2025 Mar 10;79(3):155–162. doi: 10.1007/s10858-025-00463-0

Table 1.

Amide exchange rates in Barnase (30 °C, pH 6.7). The residues listed are those for which confident rates were measured in both conditions

Residue Exchange rate (hr− 1), no betaine Exchange rate (hr− 1), 1 M betaine
11 0.057 0.0063
12 0.23 0.1
13 0.027 0.0047
14 0.0016 0.0015
15 0.0093 0.0056
17 0.18 0.0689
19 0.0024 0.0016
25 0.0016 0.0004
26 0.079 0.025
30 0.0026 0.0014
31 0.16 0.0304
33 0.032 0.0109
35 0.21 0.0751
45 0.33 0.0945
46 0.0078 0.0030
49 0.0052 0.0033
50 0.002 0.0016
51 0.0054 0.0027
56 0.0063 0.0020
75 0.0021 0.0003
76 0.0028 0.0015
87 0.047 0.016
88 0.0017 0.0015
89 0.0012 0.0017
95 0.028 0.0168
97 0.0016 0.0016
98 0.0041 0.0013
99 0.0056 0.0015