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. 2025 Aug 12;12:1624682. doi: 10.3389/fmed.2025.1624682

Table 1.

Quartiles for biomarkers and metrics.

Quartiles Troponin I (ng/L) Troponin glycation rate (TGR) Troponin glycation index (TGI) LDL (mg/dl) LDL glycation rate (LGR) LDL glycation index (LGI)
1 1.6–2.4a 1.0–1.15 1.6–2.8 60–90d 1.0–1.15 60–104
2 2.5–3.3 1.16–1.31 2.9–4.3 91–121 1.16–1.31 105–160
3 3.4–4.5/5.0b 1.32–1.50 4.4–6.75/7.5c 122–152 1.32–1.50 161–228
4 >4.5: femaleb >1.50e >6.75c 153–180 >1.50e 229–270
4 >5.0: maleb >1.50e >7.5c 153–180 >1.50e 229–270

Upper allowable limits for the calculations are: LDL: 180 mg/dl. A1c: 48 mmol/mol (6.5%). Fructosamine: 285 umol/L. Troponin I: 4.5 ng/L for females and 5 ng/L for males. a1.6 ng/L is the limit of detection (LOD) for troponin I assay (104). bROC risk cut off for females >4.5 ng/L and males >5 ng/L (65, 67, 69). cTGI >6.75 for females: > 7.5 for males. d60–80 mg/dL is concentration limiting atherosclerosis development (86). e>1.5 requires exclusionary value of A1c > 48 mmol/mol (>6.5%).