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. 2025 Jul 18;30(9):1692–1699. doi: 10.1007/s10147-025-02809-y

Table 4.

Reasons for answers about willingness to utilize the off-label drug as molecular-based recommended therapy

No cost burden Cost ¥200,000 per month (approximately $US1,300/month) Cost ¥1,000,000 per month (approximately $US6,700/month)
N % N % N %
Reasons forvery positive” and “positive”
Total number pf people 687 100 258 100 112 100
Expect the anti-tumor efficacy 458 67 192 74 67 60
Hate doing nothing 216 31 67 26 28 25
Believe I can contribute to future cancer treatment 193 28 62 24 26 23
Think my family would like it 98 14 37 14 18 16
Others 4 1 4 2 2 2
Don’t know/Don’t want to answer 38 6 13 5 12 11
Reasons for “fair”, “negative”, and “not at all”
Total number pf people 574 100 1003 100 1149 100
Too expensive NA NA 594 59 843 73
Safety concerns 183 32 181 18 177 15
Not clear about the efficacy 245 43 301 30 312 27
Cancer can’t be cured 151 26 206 21 214 19
Psychological resistance to using off-label drugs 149 26 181 18 148 13
Think my family would not like it 10 2 23 2 23 2
Others 18 3 15 2 17 2
Don’t know/Don’t want to answer 125 22 123 12 116 10

Abbrebiation NA not applicable