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. 2025 Aug 12;16:1629473. doi: 10.3389/fimmu.2025.1629473

Figure 5.

Box plot charts show ELISA IgG levels in different groups at one and six months. Groups include healthy controls, multiple myeloma, non-multiple myeloma hematological, and solid conditions. Categories are further divided by age (< 65 and ≥ 65) and doses (2 to 4 doses). Geometric means, confidence intervals, and sample sizes are noted. Significant differences are marked with p-values.

Anti-SARS-CoV-2 spike IgG levels post vaccination in serum samples from cancer and healthy cohorts within different age groups (<65 years old and ≥ 65 years old). Comparison of serum anti-spike IgG levels in healthy, multiple myeloma, non-MM hematological cancer and solid cancer cohorts within different age groups 1-month (A) and 6-months (B) post-vaccination. Anti-spike IgG levels were presented as Geometric Mean (GM) with 95% confidence intervals (95% CI). Box plots show median (horizontal bar), the first and third quartiles. Differences assessed by non-parametric Wilcoxon rank sum test. *p<0.05, **p<0.01.