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. 2025 May 20;41(5):503–513. doi: 10.1007/s43188-025-00297-w

Table 5.

The clinical chemistry of male SD rats fed with RYR for 90 days

Parameter Unit Group
Control 20% RYR 40% RYR
GGT (U/l)  < 1  < 1  < 1
ALT (U/l) 23.4 ± 4.3 16.6 ± 2.1* 18.2 ± 2.8*
AST (U/l) 92.2 ± 29.2 66.2 ± 16.3 60 ± 5.0
ALP (U/l) 360.4 ± 73.7 317.4 ± 73.3 305.4 ± 64.7
GLU (mg/dl) 120 ± 22.6 132.4 ± 34.8 103 ± 19.3
BUN (mg/dl) 12.7 ± 1.9 15.5 ± 2.8 14.2 ± 1.2
CREATININE (mg/dl) 0.272 ± 0.037 0.322 ± 0.053 0.284 ± 0.035
TP (g/dl) 6.56 ± 0.21 6.06 ± 0.38 6.00 ± 0.47
ALB (g/dl) 3.90 ± 0.24 3.62 ± 0.40 3.64 ± 0.34
T-BIL (mg/dl) 0.66 ± 0.45 0.36 ± 0.05 0.54 ± 0.43
Ca (mg/dl) 10.46 ± 0.43 10.30 ± 0.93 10.14 ± 0.40
IP (mg/dl) 8.20 ± 0.95 8.16 ± 1.01 7.84 ± 0.59
CPK (U/l) 443.0 ± 221.8 284.4 ± 108.3 231.6 ± 61.6
Na (mmol/L) 145.8 ± 3.7 150.2 ± 8.9 150.4 ± 3.8
K (mmol/L) 6.66 ± 0.71 6.28 ± 1.21 7.54 ± 0.82
Cl (mmol/L) 103.0 ± 0.7 105.4 ± 3.4 106.4 ± 0.9
TG (mg/dl) 81.4 ± 40.0 76.4 ± 20.6 91.2 ± 30.6
T-CHOL (mg/dl) 83.0 ± 15.7 80.2 ± 10.5 72.8 ± 7.1
LDL-C (mg/dl) 7.54 ± 0.84 6.90 ± 1.41 6.88 ± 1.01
HDL-C (mg/dl) 52.6 ± 10.5 49.0 ± 4.5 46.2 ± 5.2
LDH (U/l) 810.6 ± 484.9 551.2 ± 324.0 547.0 ± 229.4
TSH (ng/mL) 2.68 ± 2.10 1.58 ± 0.92 1.80 ± 1.03
T4 (ng/mL) 50.49 ± 14.61 76.17 ± 12.55 75.73 ± 51.64
T3 (ng/mL) 1.54 ± 0.27 1.61 ± 0.05 1.57 ± 0.02

GGT gamma-glutamyltransferase, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase GLU glucose, BUN blood urea nitrogen, TP total protein, ALB albumin, T-BIL total bilirubin, Ca calcium, IP inorganic phosphorus, CPK creatinine phosphokinase, Na sodium, K potassium, Cl chloride, TG triglyceride, T-CHOL total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, LDH lactate dehydrogenase, TSH thyroid stimulating hormone, T4 thyroxine, T3 triiodothyronine

All data are given as mean ± standard deviation (n = 5)

*Significantly different from control by Dunnett’s t-test at p < 0.05