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. 2025 May 19;41(5):455–475. doi: 10.1007/s43188-025-00287-y

Table 6.

Within- and between-laboratory reproducibility

Within laboratory No. of samples No. of trials Fleiss' Kappa 95% CI Z-score p value
Lab 1 11* 3 0.876 (0.647, 1.000) 5.032 < 0.001
Lab 2 12 3 1.000 (1.000, 1.000) 6.000 < 0.001
Lab 3 12 3 0.880 (0.650, 1.000) 5.278 < 0.001
Between Laboratory No. of samples No. of trials Fleiss' Kappa 95% CI Z-score p value
15* 3 0.860 (0.676, 1.000) 6.490 < 0.001

*Missing result is excluded from the sample count