Table 2.

Cost inputs

	Drug cost per infusion, €	Administration cost per infusion, €	Dosing schedule	Source
Drug costs
Avelumab 800 mg (IV)	2605.36	192.93	2 infusions per 4 weeks	Z-index, Franken et al. 2018 [28], avelumab summary of product characteristics [8]
BSC	0	0	NA	Assumption

	Unit cost, €	PFS frequency	PD frequency	Source
Resource costs
Oncologist visit	305.47	1 per month	1 per month	ZIN costing manual
Home-care	70.85		1 per month	ZIN costing manual
GP home visit	61.08		1 per month	ZIN costing manual
Terminal care costs	6545.71	Upon death		NZA DBC zorgproducten
Informal care costs	17.10	6 h	10 h	ZIN costing manual
Travel expenses	6.91	1 per month	1 per month	ZIN costing manual

BSC best supportive care, DBC drug treatment combination, GP general practitioner, IV intravenous, NA not applicable, NZA Nederlandse zorgautoriteit, OS overall survival, PD progressive disease, PFS progression-free survival, ZIN Zorginstituut Nederland